Articles Tagged With:
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Does Alkaline Phosphatase Reduce Sepsis-Associated Acute Kidney Injury?
This Phase III, international, multicenter, double-blind, randomized controlled trial did not show a reduction in 28-day all-cause mortality with ilofotase alfa (recombinant human alkaline phosphatase). However, the study showed evidence to suggest that ilofotase alfa reduced major adverse kidney events at 90 days, mainly driven by lowering the incidence of renal replacement therapy through day 90 in these patients.
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Ventilation and Oxygenation Considerations During and After Cardiopulmonary Resuscitation
With a multitude of recommendations spanning from monitoring during cardiopulmonary resuscitation (CPR) to post-arrest targeted temperature management, the specific focus of this article is to review considerations related to ventilation and oxygenation during and after CPR.
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Effect of Atrial Fibrillation Catheter Ablation on Psychological Well-Being
A randomized trial of catheter ablation vs. medical therapy for atrial fibrillation (AF) patients has shown that anxiety and depression scores are significantly reduced by catheter ablation and are associated with decreases in AF burden and improved physical symptoms.
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Long-Term Antiplatelet Therapy After PCI
The five-year follow-up of patients randomized to clopidogrel vs. aspirin monotherapy beyond one year after percutaneous coronary intervention has shown that clopidogrel is noninferior, but not superior, to aspirin for preventing the combined endpoint of adverse cardiovascular or major bleeding events.
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PFO Closure Review Shows High Proportion of Off-Label Use
In this retrospective cohort study using administrative data from a U.S. payor source, only 58.6% of patients undergoing patent foramen ovale closure had the procedure done for the approved indication of stroke or systemic embolism. A significant proportion of patients were outside the recommended age range.
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Do Patients Feel Better After Tricuspid Valve Clipping?
A further analysis of the quality-of-life parameters in a trial of tricuspid transcatheter edge-to-edge repair (T-TEER) in patients with severe symptomatic tricuspid regurgitation vs. medical therapy alone has shown that T-TEER is associated with significant benefits in physical functioning and quality of life that are sustained for one year and were proportional to the magnitude of regurgitation reduction.
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Does Anyone with Severe Aortic Stenosis Not Benefit from TAVR?
A single-center, retrospective study of low-flow low-gradient aortic stenosis patients has shown that a gradient < 20 mmHg identifies a high-risk group because of significant comorbidities that may not benefit from transcutaneous aortic valve replacement.
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Teen Pregnancies in the ED Part 1: First Trimester
This article is the first of a two-part series that focuses on an important emergency medicine topic — teenage pregnancy. In this first part, the author focuses on the unique features that affect diagnosis and management of pregnancy in adolescence. Part two will focus on obstetrical emergencies in pregnant teenagers.
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Evaluation and Management of Neck Trauma
The neck is a complex region that may have injuries that range from minor to life-threatening. An understanding of the anatomy and potential injuries is essential to optimize patient care and outcomes.
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Imported Gestational Malaria
Pregnant women can develop malaria in non-endemic areas, even when they are far removed from malaria exposure both geographically and temporally.